Some approaches to new antibacterial agents
نویسندگان
چکیده
منابع مشابه
Some approaches to new antibacterial agents
Bacteria use a number of resistance mechanisms to counter the antibacterial challenge, and one of these is the expression of transmembrane protein-based efflux pumps which can pump out antibacterials from within the cells, thus lowering the antibacterial concentration to nonlethal levels. For example, in S. aureus, the NorA pump can pump out the antibacterial alkaloid berberine and ciprofloxaci...
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Heterocyclic compounds containing a pyrimidine nucleus are of special interests due to their applications in medicinal chemistry as they are the basic skeleton of several bioactive compounds such as antifungal, antibacterial, antitumor and antitubercular. As a part of our research in the synthesis of pyrimidine derivatives containing biological activities, some new tetrahydropyrimidine derivati...
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ژورنال
عنوان ژورنال: Pure and Applied Chemistry
سال: 2007
ISSN: 1365-3075,0033-4545
DOI: 10.1351/pac200779122143